Medical uses:
Uplizna is a CD19-directed cytolytic antibody used to treat neuromyelitis optica spectrum disorder (NMOSD) in adults who test positive for AQP4 antibodies.
Recommended Dosage:
- Pre-treatment Screening: Conduct screenings for Hepatitis B virus (HBV), quantitative serum immunoglobulins, and Tuberculosis (TB) before the first dose of Uplizna.
- Pre-infusion Requirements: Before each infusion, check for active infections and premedicate patients with a corticosteroid, an antipyretic, and an antihistamine.
Administration:
- Dilution: Dilute Uplizna in 250 mL of 0.9% Sodium Chloride Injection before administration.
- Infusion: Administer as an intravenous (IV) infusion over approximately 90 minutes.
Dosage Schedule:
- Initial Dose: 300 mg IV infusion, followed by a second 300 mg IV infusion 14 days later.
- Maintenance Dose: Starting six months after the initial dose, administer a single 300 mg IV infusion every six months.
Monitoring: Closely monitor patients throughout the infusion and for at least 60 minutes after completion.
Warnings & Precautions:
Uplizna can cause infusion reactions, which may include symptoms such as nausea, headache, drowsiness, fever, shortness of breath, muscle pain, rash, or other signs. To reduce the risk of these reactions, premedicate patients with a corticosteroid, an antipyretic, and an antihistamine.
The risk of infections may increase when using other B-cell-depleting therapies. Delay Uplizna 100 mg/10 mL injection in patients with an active infection until it is resolved.
Before starting Uplizna, evaluate patients for tuberculosis (TB) risk factors and test for latent TB infection. Consider anti-tuberculosis therapy for patients with a history of latent or active TB.
Administer all immunizations according to guidelines at least 4 weeks before starting Inebilizumab-cdon. Avoid live-attenuated or live vaccines during treatment and until B-cell repletion.
Uplizna may cause fetal harm based on animal studies. Females of reproductive potential should use effective contraception during treatment and for six months after stopping Uplizna.
Documentation & Availability :
Documents required to import UPLIZNA to India?
UPLIZNA (inebilizumab-cdon) injections can be imported by patients or treating physicians on behalf of patients. The following documentation is required to import the product:
- 2 ID proofs along with PAN card details along with attested scanned copies
- Valid doctor prescription scanned copy
- Doctor’s MCI number
- Doctor’s mobile number
- Patients diagnostic reports
How is the order confirmed?
The order will be confirmed only after the receipt of:
- The above-mentioned documents and drug availability.
- Import permit if applicable.
Sourcing & Delivery:
The Rx4U team has extensive experience in sourcing UPLIZNA (Cancer Treatment Medicines) from around the world, ensuring global access to the best available treatments for our customers. We are dedicated to promptly dispensing any valid prescription. All prescriptions are verified and dispatched directly to the patient’s address. Our patients are our top priority, and we strive to improve their lives through our services.
FAQ:
What is the Generic Name for the trade name drug Uplizna®?
Inebilizumab-cdon is a Generic Name for the trade name drug Uplizna®.
What is the Manufacturer’s Name of Uplizna®?
Uplizna® is manufactured by Horizon Therapeutics.
Is Uplizna® approved by the FDA?
Yes, Uplizna® is approved by the FDA. Date of first approval: June 11, 2020.
Where can I get Uplizna® at the best price in India?
To get the best Uplizna price in India, kindly get in touch with Rx4u team.
What is the dosage and form of Uplizna® supplied?
Uplizna® is supplied as Injections: 100 mg/10 mL (10 mg/mL) solution in a single-dose vial for intravenous administration.
Where to Buy Uplizna® Injection in India?
Buy Uplizna 100 mg/10 mL injection through https://rx4u.in/
What are the most common side effects of Uplizna®?
The most common side effects of Uplizna® are arthralgia and urinary tract infection.
How much does Uplizna cost in India?
The Uplizna cost in India can vary. In order to procure this medication , you can reach out to Rx4u team.
What are the storage conditions of Uplizna®?
Store in a refrigerator at a temperature of 2 to 8°C (36 to 46°F) in the original carton to protect it from the light. It is not advisable to freeze or shake the medicine. Store vials of Uplizna upright.
Is it safe to buy Uplizna® online in India?
Yes, one can buy Uplizna 100 mg/10 mL online in India at the best price from https://rx4u.in/
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