Medical Use
Mepsevii is a recombinant human lysosomal beta glucuronidase used to treat both children and adults with mucopolysaccharidosis type VII (MPS VII), also known as Sly syndrome.
Limitations of Use:
The impact of Mepsevii on the central nervous system symptoms of MPS VII is not yet known.
Recommended Dosage: Mepsevii should be administered under the supervision of a healthcare professional who can manage anaphylaxis. Premedication is necessary 30-60 minutes before starting the infusion.
The recommended dose of Mepsevii is 4 mg per kg (4 mg/kg), given by intravenous infusion every two weeks.
The infusion should be administered over about 4 hours. During the first hour, infuse 2.5% of the total volume. After the first hour, the infusion rate can be increased to complete the remaining volume over the next 3 hours, as tolerated.
Warning & Precautions
Anaphylaxis, a potentially life-threatening reaction, may occur during Vestronidase alfa infusion. Therefore, it should be administered under the supervision of a healthcare professional capable of managing such reactions. Patients should be monitored for one hour after the infusion. If severe systemic reactions, including anaphylaxis, occur, the infusion should be stopped immediately and appropriate medical treatment provided.
Before discharge, patients should be informed about the signs and symptoms of anaphylaxis and advised to seek immediate medical help if they experience any symptoms. The risks and benefits of re-administering Vestronidase alfa after an anaphylactic reaction should be carefully considered.
If you are pregnant, think you might be pregnant, or plan to become pregnant, inform your healthcare provider before receiving Mepsevii 10 mg/5 mL (2 mg/mL), as there is insufficient data on its effects on an unborn baby.
Similarly, if you are breastfeeding or plan to breastfeed, let your healthcare provider know before receiving Vestronidase alfa 10 mg/5 mL (2 mg/mL), as it is not known whether the drug passes into breast milk. Discuss the best feeding options for your baby with your healthcare provider while on this treatment.
If you have any allergies to Vestronidase alfa, its components, or other substances, inform your healthcare provider about the allergy and the symptoms you experienced. This medication may interact with other drugs or health conditions.
Documentation Availability
Documents required to import MEPSEVII to India?
MEPSEVII (Vestronidase alfa-vjbk) Injection can be imported by patients or treating physicians on behalf of patients. The following documentation is required to import the product:
- (i)2 ID proofs along with PAN card details along with attested scanned copies
- (ii)Valid doctor prescription scanned copy
- (iii)Doctor’s MCI number
- (iv)Doctor’s mobile number
- (v)Patients diagnostic reports
How is the order confirmed?
The order will be confirmed only after the receipt of:
- (i)The above-mentioned documents and drug availability.
- (ii)Import permit if applicable.
Sourcing & Delivery
The Rx4U team has extensive experience in sourcing MEPSEVII (Cancer Treatment Medicines) from around the world, ensuring global access to the best available treatments for our customers. We are dedicated to promptly dispensing any valid prescription. All prescriptions are verified and dispatched directly to the patient’s address. Our patients are our top priority, and we strive to improve their lives through our services.
FAQ
What is the Generic Name for Mepsevii®?
The generic name for Mepsevii® is Vestronidase alfa-vjbk.
Who Manufactures Mepsevii®?
Mepsevii® is produced by Ultragenyx Pharmaceutical Inc.
Is Mepsevii® FDA Approved?
Yes, Mepsevii® received FDA approval on November 15, 2017.
What is the Dosage and Form of Mepsevii®?
Mepsevii® is available as an injection: 10 mg/5 mL (2 mg/mL) in a single-dose vial for intravenous use.
What Are the Common Side Effects of Mepsevii®?
Common side effects include rash, infusion site extravasation, diarrhea, anaphylaxis, infusion site swelling, peripheral swelling, and itching.
How Much Does Mepsevii® Cost in India?
The cost of Mepsevii® in India varies. For authentic procurement, contact Rx4u team.
What Are the Storage Conditions for Mepsevii®?
Store Mepsevii® in a refrigerator at 2 to 8°C (36 to 46°F). Do not freeze or shake. Keep it protected from light.
Is It Safe to buy Mepsevii® Online from India?
Yes, you can safely purchase Mepsevii® online in India through https://rx4u.in/.
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