Adakveo (Crizanlizumab-tmca)

Adakveo (Crizanlizumab-tmca)

Adakveo

Crizanlizumab-tmca

Injection: 100 mg/10 mL solution in a single-dose vial

Novartis

Medical Use

Adakveo is a selectin blocker used to reduce the frequency of painful crises in adults and pediatric patients aged 16 years and older with sickle cell disease (SCD).

Recommended Dosage: The recommended dosage of Adakveo is 5 mg per kg, administered via intravenous (IV) infusion over 30 minutes at Week 0, Week 2, and then every 4 weeks thereafter.

Missed Dose Instructions: If a dose is missed, administer it as soon as possible. If given within 14 days of the missed dose, continue with the regular dosing schedule. If administered more than 14 days after the missed dose, resume dosing every 28 days (4 weeks) thereafter. Adakveo can be used with or without hydroxyurea.