Medical Use
Blenrep is a BCMA-targeted antibody and microtubule inhibitor conjugate used for treating adult patients with relapsed or refractory multiple myeloma (MM). It is indicated for those who have undergone at least four prior therapies, including a proteasome inhibitor, an anti-CD38 monoclonal antibody, and an immunomodulatory agent.
Recommended Dosage:
- -Administer Blenrep at a dose of 2.5 mg/kg of actual body weight.
- -It should be given as an intravenous infusion over approximately 30 minutes.
- -The infusion is repeated once every 3 weeks until disease progression or the occurrence of unacceptable toxicity.
Warning & Precautions
Conduct baseline ophthalmic evaluations (visual acuity and slit lamp) before starting treatment, prior to each dose, and promptly if there are any worsening signs or symptoms. Perform these baseline evaluations within three weeks before the first dose. Follow-up examinations should be done at least one week after the last dose and within two weeks before the next dose.
If necessary, withhold the BLENREP 100 mg injection until improvement is observed, then resume at the same or a reduced dose, or consider permanent discontinuation based on the severity of the condition.
Advise patients to use preservative-free lubricant eye drops at least four times daily, starting with the first infusion and continuing until the end of treatment. Patients should avoid using contact lenses unless instructed by an ophthalmologist.
Changes in visual acuity may affect the ability to drive or read. Patients should be advised to exercise caution when driving or operating machinery.
Monitor patients for infusion-related reactions. For Grade 2 or 3 reactions, interrupt the infusion and provide supportive treatment. Once symptoms resolve, resume at a reduced infusion rate.
Due to its mechanism of action, Belantamab Mafodotin can cause fetal harm if administered to a pregnant woman, as it contains a genotoxic compound (the microtubule inhibitor, monomethyl auristatin F) and targets actively dividing cells. Women should not breastfeed during treatment with Belantamab Mafodotin-blmf and for three months after the last dose.
Documentation Availability
Documents required to import BLENREP to India?
BLENREP (Belantamab Mafodotin-blmf) can be imported by patients or treating physicians on behalf of patients. The following documentation is required to import the product:
- (i)2 ID proofs along with PAN card details along with attested scanned copies
- (ii)Valid doctor prescription scanned copy
- (iii)Doctor’s MCI number
- (iv)Doctor’s mobile number
- (v)Patients diagnostic reports
How is the order confirmed?
The order will be confirmed only after the receipt of:
- (i)The above-mentioned documents and drug availability.
- (ii)Import permit if applicable.
Sourcing & Delivery
The Rx4U team has extensive experience in sourcing BLENREP (Cancer Treatment Medicines) from around the world, ensuring global access to the best available treatments for our customers. We are dedicated to promptly dispensing any valid prescription. All prescriptions are verified and dispatched directly to the patient’s address. Our patients are our top priority, and we strive to improve their lives through our services.
FAQ
What is the Generic Name for Blenrep®?
The generic name for Blenrep® is Belantamab Mafodotin-blmf.
Who manufactures Blenrep®?
Blenrep® is manufactured by GlaxoSmithKline.
Is Blenrep® FDA approved?
Yes, Blenrep® was approved by the FDA on August 5, 2020.
What is Blenrep® injection used for?
Blenrep® injection is an FDA-approved medication for treating patients with relapsed or refractory multiple myeloma (RRMM).
What is the dosage form of Blenrep®?
Blenrep® is supplied as a 100 mg lyophilized powder in a single-dose vial for reconstitution and further dilution.
What are the most common side effects of Blenrep®?
Common side effects include nausea, keratopathy (changes in the corneal epithelium), decreased visual acuity, fever (pyrexia), infusion-related reactions, blurred vision, and fatigue.
How should Blenrep® be stored?
Store Blenrep® vials refrigerated at 36°F to 46°F (2°C to 8°C). As it is a hazardous agent, follow special handling and disposal procedures.
Is it safe to buy Blenrep® online in India?
Yes, you can safely purchase Blenrep® online in India through https://rx4u.in/.
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