Medical Use
Bosulif (bosutinib) is a kinase inhibitor used to treat chronic myelogenous leukemia (CML) in both adults and children aged 1 year and older. It is prescribed for patients in the chronic phase of Philadelphia chromosome-positive (Ph+) CML, whether they are newly diagnosed or have not responded well to previous treatments. Additionally, Bosulif is used in adults with advanced stages of Ph+ CML, such as the accelerated or blast phase, when they have shown resistance or intolerance to prior therapies.
Recommended Dosage:
- -Take Bosulif once a day with food.
- -Swallow the tablets whole—do not cut, crush, break, or chew them.
- -Continue using Bosulif until your doctor advises stopping due to disease progression or side effects.
Capsules:
- -Swallow capsules whole.
- -If you have trouble swallowing capsules, you can open them and mix the contents with applesauce or yogurt. However, this mixture should not replace a full meal.
Missed Dose:
- -If you miss a dose and more than 12 hours have passed, skip that dose and take your next scheduled dose at the usual time the following day.
Dosage Guidelines:
- -Adults with Newly-Diagnosed CP Ph+ CML: 400 mg orally once daily with food.
- -Adults with CP, AP, or BP Ph+ CML with Resistance or Intolerance to Prior Therapy: 500 mg orally once daily with food.
- -Pediatric Patients with Newly-Diagnosed CP Ph+ CML or with CP Ph+ CML with Resistance or Intolerance to Prior Therapy: 300 mg/m² orally once daily with food for newly diagnosed cases, and 400 mg/m² orally once daily with food for resistant or intolerant cases.
Warning & Precautions
Bosutinib may cause gastrointestinal issues such as diarrhea, nausea, vomiting, and stomach pain, which can sometimes be severe. Staying hydrated is crucial, and you should consult your doctor if these symptoms become bothersome.
Blood Cell Counts: This medication can lower your blood cell counts, increasing the risk of infections, anemia, or bleeding. Regular blood tests are essential to monitor your blood cell levels. If you notice unusual bruising, bleeding, or signs of infection like fever, contact your healthcare provider immediately.
Liver Health: Bosutinib may affect your liver. Symptoms of liver problems include yellowing of the skin or eyes (jaundice), dark urine, or pain in the upper right side of your abdomen. Regular liver function tests are important to detect any issues early.
Heart Health: This medication can cause heart problems, such as heart failure or irregular heartbeats. If you experience chest pain, rapid heartbeat, shortness of breath, or swelling in your legs, seek medical attention right away.
Fluid Retention: Bosutinib can cause your body to retain excess fluid, leading to swelling, especially in the hands, feet, or around the eyes. Report any significant swelling or sudden weight gain to your doctor.
Kidney Health: Kidney problems can occur with Bosulif. Symptoms might include decreased urine output, swelling, or unexplained fatigue. Your doctor will monitor your kidney function with blood tests during treatment.
Pregnancy and Breastfeeding: Bosulif can harm an unborn baby. Women who are pregnant, planning to become pregnant, or could become pregnant should avoid taking this medication and use effective birth control during treatment. It is not known if Bosulif passes into breast milk, so women should not breastfeed while taking this medication. Discuss alternatives with your healthcare provider.
Documentation Availability
Documents required to import BOSULIF to India?
BOSULIF (bosutinib) can be imported by patients or treating physicians on behalf of patients. The following documentation is required to import the product:
- (i)2 ID proofs along with PAN card details along with attested scanned copies
- (ii)Valid doctor prescription scanned copy
- (iii)Doctor’s MCI number
- (iv)Doctor’s mobile number
- (v)Patients diagnostic reports
How is the order confirmed?
The order will be confirmed only after the receipt of:
- (i)The above-mentioned documents and drug availability.
- (ii)Import permit if applicable.
Sourcing & Delivery
The Rx4U team has extensive experience in sourcing BOSULIF (a cancer treatment medication) around the world, ensuring global access to the best available treatments for our customers. We are dedicated to promptly dispensing any valid prescription. All prescriptions are verified and dispatched directly to the patient’s address. Our patients are our top priority, and we strive to improve their lives through our services.
FAQ
What is the Generic Name for Bosulif®?
The generic name for Bosulif® is bosutinib.
Who Manufactures Bosulif®?
Bosulif® is manufactured by Pfizer.
Is Bosulif® FDA Approved?
Yes, Bosulif® received FDA approval on September 4, 2012.
What Dosage Forms and Strengths are Available for Bosulif®?
Bosulif® is available in tablet form, with strengths of 100 mg and 150 mg for oral administration.
What are the Common Side Effects of Bosulif®?
Common side effects include vomiting, nausea, diarrhea, abdominal pain, rash, fatigue, headache, fever, liver dysfunction, decreased appetite, respiratory tract infection, and constipation.
How Much Does Bosulif® Cost in India?
Prices can vary due to market conditions and regulatory changes. For the latest pricing, contact the Rx4u team.
What are the Storage Conditions for Bosulif®?
Store Bosulif® at 20°C to 25°C (68°F to 77°F), with permissible excursions between 15°C and 30°C (59°F to 86°F). Keep it in the original container.
How to order Bosulif® online in India?
Bosulif® can be ordered online in India through https://rx4u.in/.
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