Medical Use
Idhifa is a medication that inhibits isocitrate dehydrogenase-2 (IDH2) and is used to treat adult patients with relapsed or refractory acute myeloid leukemia (AML) who have an IDH2 mutation.
Recommended Dosage:
- -Patient Selection: Ensure patients have IDH2 mutations in their blood or bone marrow before starting treatment with Idhifa.
- -Starting Dose: The initial dose is 100 mg taken orally once daily, with or without food, until the disease progresses or unacceptable toxicity occurs.
- -Treatment Duration: For patients without disease progression or unacceptable toxicity, continue treatment for at least six months to allow time for a clinical response.
- -Administration Instructions: Do not split or crush the tablets. Take the 100 mg tablets orally every day without interruption.
- -Missed Dose: If a dose is missed, vomited, or not taken at the usual time, take it as soon as possible on the same day and resume the regular schedule the next day.
Warning & Precautions
Before starting Enasidenib, evaluate blood counts and blood chemistries for leukocytosis and tumor lysis syndrome (TLS). Continue monitoring at least every 14 days for the first three months of treatment, and promptly manage any abnormalities.
Differentiation Syndrome: Patients on Enasidenib may develop differentiation syndrome, which can be fatal or life-threatening if untreated. This syndrome is associated with the rapid proliferation and differentiation of myeloid cells. If differentiation syndrome occurs, initiate oral or intravenous corticosteroids (e.g., 10 mg dexamethasone every 12 hours) and provide hemodynamic monitoring until improvement. Hospitalization is necessary for close observation and evaluation, especially for patients with pulmonary or renal manifestations.
Pregnancy and Contraception: Enasidenib 100 mg can cause harm to an embryo or fetus if taken by a pregnant woman. Males with female partners of reproductive age should use effective contraception during treatment and for at least 30 days after the last dose. Pregnant women, those who become pregnant while on Enasidenib, or male patients with pregnant partners should be informed of the potential risks to the fetus.
Breastfeeding: Women should not breastfeed during treatment with Enasidenib and for at least 30 days after the final dose.
Documentation Availability
Documents required to import IDHIFA to India?
IDHIFA (enasidenib) tablets can be imported by patients or treating physicians on behalf of patients. The following documentation is required to import the product:
- (i)2 ID proofs along with PAN card details along with attested scanned copies
- (ii)Valid doctor prescription scanned copy
- (iii)Doctor’s MCI number
- (iv)Doctor’s mobile number
- (v)Patients diagnostic reports
How is the order confirmed?
The order will be confirmed only after the receipt of:
- (i)The above-mentioned documents and drug availability.
- (ii)Import permit if applicable.
Sourcing & Delivery
The Rx4U team has extensive experience in sourcing IDHIFA (Cancer Treatment Medicines) from around the world, ensuring global access to the best available treatments for our customers. We are dedicated to promptly dispensing any valid prescription. All prescriptions are verified and dispatched directly to the patient’s address. Our patients are our top priority, and we strive to improve their lives through our services.
FAQ
What is the Generic Name for Idhifa®?
The generic name for Idhifa® is Enasidenib.
Who Manufactures Idhifa®?
Idhifa® is manufactured by Celgene Corporation.
Is Idhifa® FDA Approved?
Yes, Idhifa® received FDA approval on August 1, 2017.
Where Can I Find the Best Price for Idhifa® in India?
For the best price on Idhifa® (Enasidenib) in India, contact The Rx4u team.
What is the Dosage and Form of Idhifa®?
Idhifa® is available in tablet form, with doses of 50 mg or 100 mg for oral administration.
What are the Common Side Effects of Idhifa®?
Common side effects include elevated bilirubin, nausea, vomiting, diarrhea, and decreased appetite.
How Should Idhifa® be Stored?
Store Idhifa® at 20-25°C (68-77°F), with permissible excursions between 15-30°C (59-86°F). Keep the bottle tightly closed and store it in the original bottle with a desiccant canister to protect from moisture.
Is it safe to buy Idhifa® online in India?
Yes, you can safely purchase Idhifa® online in India through https://rx4u.in/.
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