Jaypirca(pirtobrutinib)

Jaypirca(pirtobrutinib)

Jaypirca Tablets

Pirtobrutinib

Tablets: 50 mg, 100 mg

Eli Lilly and Company

Medical Use

Jaypirca is a kinase inhibitor used to treat adult patients with relapsed or refractory mantle cell lymphoma (MCL) who have undergone at least two lines of systemic therapy, including a BTK inhibitor. This indication has received accelerated approval based on response rates, with continued approval dependent on confirmatory trials verifying clinical benefits.

Dosage

Recommended Dosage: Take 200 mg orally once daily. Swallow the tablet whole with water, with or without food. Do not cut, crush, or chew the tablets.

Managing Toxicity: Toxicity can be managed by interrupting treatment, reducing the dosage, or discontinuing use as necessary.

Patients with Severe Renal Impairment: Reduce the dosage for patients with severe renal impairment.

Contraindications: None.