Medical Use
Reblozyl is an erythroid maturation agent used to treat:
- Anemia in adults with beta (β) thalassemia who require regular red blood cell (RBC) transfusions.
- Anemia in adults with very low- to intermediate-risk myelodysplastic syndromes with ring sideroblasts (MDS-RS) or myelodysplastic/myeloproliferative neoplasm with ring sideroblasts and thrombocytosis (MDS/MPN-RS-T), who have failed an erythropoiesis-stimulating agent and need two or more RBC units over 8 weeks.
Limitations of Use: Reblozyl is not intended as a substitute for RBC transfusions in patients needing immediate anemia correction.
Recommended Dosage: The starting dose is 1 mg/kg administered subcutaneously every 3 weeks for patients with beta thalassemia. Before each dose, review the patient’s hemoglobin levels and transfusion history, and adjust the dose based on response.
Discontinue treatment if there is no reduction in transfusion burden after 9 weeks (3 doses) at the maximum dose or if unacceptable toxicity occurs. If a dose is missed or delayed, administer it as soon as possible and continue with the regular schedule, ensuring at least three weeks between doses.
Warning & Precautions
Before each administration of luspatercept-aamt injection, assess and review hemoglobin levels. If a red blood cell transfusion occurred prior to dosing, use the pre-transfusion hemoglobin level for dose evaluation.
In adult patients with beta thalassemia, thromboembolic events (TEEs) have been reported in those treated with Reblozyl. Monitor for signs and symptoms of TEEs and initiate treatment promptly if they occur.
Hypertension has been observed in patients receiving Reblozyl. Blood pressure should be checked before each dose. Manage new or worsening hypertension with appropriate antihypertensive medications.
Animal reproductive studies indicate that Reblozyl 75 mg injection may cause fetal harm if administered to a pregnant woman. Females of reproductive potential should use effective contraception during treatment and for at least three months after the final dose.
Documentation Availability
Documents required to import REBLOZYL to India?
REBLOZYL (luspatercept-aamt) injections can be imported by patients or treating physicians on behalf of patients. The following documentation is required to import the product:
- (i)2 ID proofs along with PAN card details along with attested scanned copies
- (ii)Valid doctor prescription scanned copy
- (iii)Doctor’s MCI number
- (iv)Doctor’s mobile number
- (v)Patients diagnostic reports
How is the order confirmed?
The order will be confirmed only after the receipt of:
- (i)The above-mentioned documents and drug availability.
- (ii)Import permit if applicable.
Sourcing & Delivery
The Rx4U team has extensive experience in sourcing REBLOZYL (Cancer Treatment Medicines) from around the world, ensuring global access to the best available treatments for our customers. We are dedicated to promptly dispensing any valid prescription. All prescriptions are verified and dispatched directly to the patient’s address. Our patients are our top priority, and we strive to improve their lives through our services.
FAQ
What is the generic name for the trade name drug Reblozyl®?
The generic name for Reblozyl® is Luspatercept–aamt.
Who manufactures Reblozyl®?
Reblozyl® is manufactured by Celgene Corporation.
Is Reblozyl® FDA approved?
Yes, Reblozyl® received FDA approval on November 8, 2019.
What is the dosage and form of Reblozyl®?
Reblozyl® is available as an injection in two dosages: 25 mg and 75 mg lyophilized powder, which needs to be reconstituted for subcutaneous administration.
What are the common side effects of Reblozyl®?
Common side effects include cough, fatigue, headache, joint pain, dizziness/vertigo, musculoskeletal pain, nausea, diarrhea, abdominal pain, shortness of breath, and hypersensitivity.
How much does Reblozyl® cost in India?
The cost of Reblozyl® in India is relatively lower and can vary. For authentic procurement, you can reach out to the Rx4u team.
What are the storage conditions for Reblozyl®?
Reblozyl® should be stored in its original carton, refrigerated at 2°C to 8°C (36°F to 46°F), and protected from light. Do not freeze.
Is it safe to buy Reblozyl®?online in India?
Yes, you can safely purchase Reblozyl® online in India through https://rx4u.in/.
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