Korsuva (Difelikefalin)

Korsuva (Difelikefalin)

Korsuva

Difelikefalin

Injection: 65 mcg /1.3 mL (50 mcg/mL) of difelikefalin

Cara Therapeutics, Inc.

Medical Use

Korsuva is a kappa opioid receptor agonist used to treat moderate-to-severe itching (pruritus) in adults with chronic kidney disease (CKD-aP) who are undergoing hemodialysis (HD). It is not intended for use in patients undergoing peritoneal dialysis.

Recommended Dosage : 

Administer Korsuva at a dose of 0.5 mcg per kg via intravenous bolus injection into the venous line of the dialysis circuit after each hemodialysis session. If a hemodialysis session is missed, resume Korsuva treatment after the next session.

Do not mix or dilute the Korsuva injection (65 mcg/1.3 mL, 50 mcg/mL) before administration. Use the medication within 60 minutes of preparing the syringe.