Medical Use
Livmarli is the only FDA-approved medication and an ileal bile acid transporter (IBAT) inhibitor commonly used to treat cholestatic pruritus (itching) in patients with Alagille syndrome (ALGS) who are 12 months and older.
Recommended Dosage :
If you are taking bile acid-binding resins, Livmarli should be taken at least four hours before or after the resin. The recommended dosage is 380 mcg per kg once daily, taken 30 minutes before the first meal of the day. Start with 190 mcg per kg taken orally once daily; after one week, increase to 380 mcg per kg once daily, as tolerated. For those weighing over 70 kg, the maximum daily dose is 3 mL or 28.5 mg.
If a dose is vomited or missed, it should be taken as soon as possible within 12 hours of the usual time. If more than 12 hours have passed, skip the missed dose and continue with the regular dosing schedule.
Warning & Precautions
Baseline liver tests should be conducted, and patients must be monitored throughout treatment. If abnormalities arise without other causes, consider reducing the dose or pausing treatment. Discontinue treatment for persistent or recurrent liver test abnormalities.
Livmarli has not been evaluated in ALGS patients with cirrhosis. Monitor patients on Livmarli 9.5 mg oral solution for liver test elevations and liver-related toxicity.
Common side effects in patients treated with Maralixibat include vomiting, diarrhea, and abdominal pain. If these occur, consider dose reduction or interruption. Monitor for dehydration and treat promptly if vomiting or diarrhea occurs.
ALGS patients may have a deficiency in fat-soluble vitamins, which this medication can affect. Obtain serum FSV levels and monitor throughout therapy, along with any clinical symptoms. If a deficiency is detected, supplement with fat-soluble vitamins. If the deficiency persists or worsens despite supplementation, consider discontinuing Livmarli.
Documentation Availability
Documents required to import LIVMARLI to India?
LIVMARLI (maralixibat) oral solution can be imported by patients or treating physicians on behalf of patients. The following documentation is required to import the product:
- (i)2 ID proofs along with PAN card details along with attested scanned copies
- (ii)Valid doctor prescription scanned copy
- (iii)Doctor’s MCI number
- (iv)Doctor’s mobile number
- (v)Patients diagnostic reports
How is the order confirmed?
The order will be confirmed only after the receipt of:
- (i)The above-mentioned documents and drug availability.
- (ii)Import permit if applicable.
Sourcing & Delivery
The Rx4U team has extensive experience in sourcing LIVMARLI (Cancer Treatment Medicines) from around the world, ensuring global access to the best available treatments for our customers. We are dedicated to promptly dispensing any valid prescription. All prescriptions are verified and dispatched directly to the patient’s address. Our patients are our top priority, and we strive to improve their lives through our services.
FAQ
What is the generic name for the trade name drug Livmarli®?
The generic name for Livmarli® is maralixibat.
Who manufactures Livmarli®?
Livmarli® is produced by Mirum Pharmaceuticals, Inc.
Is Livmarli® FDA approved?
Yes, Livmarli® was approved by the FDA on September 29, 2021.
Where can I get Livmarli® at the best price in India?
For the best price on Livmarli® in India, contact Rx4U team.
What dosage and form is Livmarli® available in?
Livmarli® is available as an oral solution with 9.5 mg of maralixibat per mL.
What are the most common side effects of Livmarli®?
Common side effects include vomiting, diarrhea, abdominal pain, fat-soluble vitamin deficiency, gastrointestinal bleeding, liver test abnormalities, and bone fractures.
How much does Livmarli® cost in India?
The cost of Livmarli® in India can vary. To purchase this IBAT inhibitor, you can order through https://rx4u.in/.
What are the storage conditions for Livmarli®?
Store Livmarli® between 20 and 25°C (68 and 77°F), with excursions permitted between 15 and 30°C (59 and 86°F). Discard any remaining medicine 45 days after first opening the bottle.
Is it safe to buy Livmarli® online from India?
Yes, you can safely purchase Livmarli® online in India through https://rx4u.in/.
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