Nextstellis (Drospirenone and Estetrol)

Nextstellis (Drospirenone and Estetrol)

Nextstellis

Drospirenone and Estetrol

28 Tablets: 3 mg/14.2 mg

Mayne Pharma US

Medical Use

Nextstellis is the first and only FDA-approved oral contraceptive that combines drospirenone (a progestin) and estetrol (an estrogen) to prevent pregnancy. It is unique as the first oral contraceptive to contain E4, which is derived from a plant source and selectively acts on tissues. This helps support the health of the uterus, vagina, and bones while having minimal impact on the liver and breast tissue.

Note: Nextstellis may be less effective for women with a body mass index (BMI) of 30 or higher. Its safety and effectiveness in women with a BMI of 35 or higher are not known.

Recommended Dosage: Take one pill daily for 28 consecutive days: one pink active tablet for the first 24 days, followed by one white inactive tablet for the next four days. The tablets should be taken orally at the same time each day, with or without food.

If vomiting or severe diarrhea occurs within 3 to 4 hours after taking an active pill, take another active pill as soon as possible, ideally within 12 hours of the usual time. If more than two tablets are missed, follow the instructions for missed doses, which may include using a backup non-hormonal contraceptive method.