Medical Use
Evkeeza is an injectable medication that inhibits ANGPTL3 (angiopoietin-like 3). It is used alongside other LDL-C (low-density lipoprotein cholesterol) lowering treatments to manage homozygous familial hypercholesterolemia (HoFH) in adults and children aged 12 and older.
Dosage Instructions:
The recommended dosage is 15 mg/kg, administered via intravenous (IV) infusion every 4 weeks. Ensure that Evkeeza is not mixed with other medications or administered simultaneously through the same infusion line.
Administration Notes :
If a patient experiences side effects such as hypersensitivity reactions, the infusion rate may need to be adjusted, paused, or stopped.
Missed Dose :
If a dose is missed, it should be administered as soon as possible. To maintain effectiveness, schedule the medication monthly from the last dose.
Warning & Precautions
Assess low-density lipoprotein-cholesterol (LDL-C) levels as clinically indicated. The LDL-C lowering effect of Evkeeza (Evinacumab-dgnb) can be observed as early as 14 days after starting treatment.
Contraindications: Evkeeza 15 mg/mL injection should not be used by individuals with a history of serious hypersensitivity reactions to this medication or any of its components. Serious hypersensitivity reactions, including anaphylaxis, have been reported.
Pregnancy Warning: Studies suggest that Evkeeza may cause fetal harm if administered to pregnant patients. Individuals who could become pregnant should use effective contraception during treatment and for at least 5 months after the final dose.
Breastfeeding Considerations: It is unclear if evinacumab is excreted in human milk. Human IgGs can be present in breast milk during the first few days postpartum, decreasing to low levels soon after. Therefore, there is a potential risk to the breastfed infant during this period. Afterward, Evkeeza may be used while breastfeeding if clinically necessary.
Documentation Availability
Documents required to import EVKEEZA to India?
EVKEEZA (evinacumab-dgnb) injections can be imported by patients or treating physicians on behalf of patients. The following documentation is required to import the product:
- (i)2 ID proofs along with PAN card details along with attested scanned copies
- (ii)Valid doctor prescription scanned copy
- (iii)Doctor’s MCI number
- (iv)Doctor’s mobile number
- (v)Patients diagnostic reports
How is the order confirmed?
The order will be confirmed only after the receipt of:
- (i)The above-mentioned documents and drug availability.
- (ii)Import permit if applicable.
Sourcing & Delivery
The Rx4U team has extensive experience in sourcing EVKEEZA (Cancer Treatment Medicines) from around the world, ensuring global access to the best available treatments for our customers. We are dedicated to promptly dispensing any valid prescription. All prescriptions are verified and dispatched directly to the patient’s address. Our patients are our top priority, and we strive to improve their lives through our services.
FAQ
What is the Generic Name for the trade name drug Evkeeza®?
Evinacumab-dgnb is a Generic Name for the trade name drug Evkeeza®.
What is the Manufacturer’s Name of Evkeeza®?
Evkeeza® is manufactured by Regeneron Pharmaceuticals, Inc.
Is Evkeeza® approved by the FDA?
Yes, Evkeeza® is approved by the FDA. Date of approval: February 11, 2021.
What is the dosage and form of Evkeeza® supplied?
Evkeeza® is supplied as Injection: 345 mg/2.3 mL (150 mg/mL) & 1,200 mg/8 mL (150 mg/mL) solution in single-dose vials for intravenous use.
What are the most common side effects of Evkeeza®?
The most common side effects of Evkeeza® are nasopharyngitis, dizziness, influenza-like illness, nausea, and rhinorrhea.
How much does Evkeeza® cost in India?
Evkeeza cost in India is less and can vary. In order to procure this drug, reach out to Rx4u team.
What are the storage conditions of Evkeeza®?
Store this medicine in a refrigerator at 2 to 8 °C (36 to 46 °F). Store the vial in the original carton in order to protect it from light. Neither freeze nor shake it.
Is it safe to buy Evkeeza® online from India?
Yes, you can buy Evkeeza from India at the best price from https://rx4u.in/
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