Medical Use
Onpattro contains a small interfering RNA that targets transthyretin and is used to treat polyneuropathy in adults with hereditary transthyretin-mediated amyloidosis.
Recommended Dosage: Onpattro is available as a liquid in a single-dose vial and must be administered by a healthcare professional via intravenous (IV) infusion. The dosage depends on the patient’s body weight.
- For patients under 100 kg, the recommended dose is 0.3 mg/kg every 3 weeks.
- For patients 100 kg or more, the recommended dose is 30 mg every 3 weeks.
Missed Dose: If a dose is missed, it should be administered as soon as possible.
- If administered within 3 days of the missed dose, continue with the original schedule.
- If more than 3 days have passed, continue dosing every 3 weeks from the new administration date.
Warning & Precautions
Premedication and Monitoring: Patients should be premedicated at least 60 minutes before starting the Onpattro infusion. During the infusion, monitor patients for any signs or symptoms of infusion-related reactions (IRRs). If an IRR occurs, slow down or interrupt the infusion and provide appropriate medical management, such as corticosteroids or other symptomatic treatments.
Handling Infusion Interruptions: If the Onpattro 10 mg infusion is interrupted, consider resuming at a reduced rate only if the signs and symptoms have resolved. For severe or life-threatening IRRs, discontinue the infusion and do not resume.
Vitamin A Levels: Onpattro therapy can reduce serum vitamin A levels. Patients should take vitamin A supplements at the recommended daily allowance. Do not exceed this dosage to normalize serum vitamin A levels, as serum levels do not reflect the total body vitamin A.
Ophthalmologic Monitoring: Patients on Onpattro 2 mg should see an ophthalmologist if they develop symptoms of vitamin A deficiency, such as night blindness.
Pregnancy and Breastfeeding: Patients should inform their healthcare provider if they are pregnant or planning to become pregnant while on Onpattro. Female patients of childbearing age should be aware of the potential risks to the fetus. It is not known if Patisiran passes into breast milk or affects milk production. Patients who are breastfeeding or plan to breastfeed should discuss with their doctor whether Patisiran is suitable for them.
Documentation Availability
Documents required to import ONPATTRO to India?
ONPATTRO (Patisiran) lipid complex injection can be imported by patients or treating physicians on behalf of patients. The following documentation is required to import the product:
- (i)2 ID proofs along with PAN card details along with attested scanned copies
- (ii)Valid doctor prescription scanned copy
- (iii)Doctor’s MCI number
- (iv)Doctor’s mobile number
- (v)Patients diagnostic reports
How is the order confirmed?
The order will be confirmed only after the receipt of:
- (i)The above-mentioned documents and drug availability.
- (ii)Import permit if applicable.
Sourcing & Delivery
The Rx4U team has extensive experience in sourcing ONPATTRO (Cancer Treatment Medicines) from around the world, ensuring global access to the best available treatments for our customers. We are dedicated to promptly dispensing any valid prescription. All prescriptions are verified and dispatched directly to the patient’s address. Our patients are our top priority, and we strive to improve their lives through our services.
FAQ
What is the Generic Name for Onpattro®?
The generic name for Onpattro® is Patisiran.
Who Manufactures Onpattro®?
Onpattro® is manufactured by Alnylam Pharmaceuticals, Inc.
Is Onpattro® FDA Approved?
Yes, Onpattro® received FDA approval on August 10, 2018.
Where to Buy Onpattro® at the Best Price in India?
For the best price on Onpattro® in India, contact Rx4U team.
What is the Dosage and Form of Onpattro®?
Onpattro® is available as a Lipid Complex Injection: 10 mg/5 mL (2 mg/mL) in a single-dose vial for intravenous use.
What are the Common Side Effects of Onpattro®?
The most common side effects include upper respiratory tract infections and infusion-related reactions.
What is the cost of Onpattro® in India?
Onpattro® is reasonably priced in India. For authentic procurement, you can reach out to https://rx4u.in/
What is the storage conditions for Onpattro®?
Store at 2 to 8°C (36 to 46°F). Do not freeze. If frozen, discard the vials. If refrigeration is unavailable, store at room temperature up to 25°C (77°F) for up to 2 weeks (14 days).
Is it Safe to Buy Onpattro® Online from India?
Yes, you can safely buy Onpattro® 10 mg/5 mL (2 mg/mL) online from Indian Pharma Network if it is not approved or available in your country.
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